Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients.

@article{Somfay2002EffectOH,
  title={Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients.},
  author={Attila Somfay and J{\'a}nos P{\'o}rsz{\'a}sz and Sang-Moo Lee and Richard H Casaburi},
  journal={Chest},
  year={2002},
  volume={121 2},
  pages={393-400}
}
STUDY OBJECTIVES The slow oxygen uptake (VO(2)) kinetics observed in COPD patients is a manifestation of skeletal muscle dysfunction of multifactorial origin. We determined whether oxygen supplementation during exercise makes the dynamic VO(2) response faster and reduces transient lactate increase. DESIGN Ten patients with severe COPD (ie, mean [+/- SD] FEV(1), 31 +/- 10% predicted) and 7 healthy subjects of similar age performed four repetitions of the transition between rest and 10 min of… CONTINUE READING
34 Citations
42 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Effects of supplemental oxygen on peripheral hemodynamics and metabolism during exercise in COPD [abstract

  • M Simon, P LeBlanc, J Jobin
  • Am J Respir Crit Care Med
  • 1999

Histochemical and morphological characteristics of the vastus lateralis muscle in COPD patients

  • C Simard, F Maltais, P Leblanc
  • Med Sci Sports Exerc
  • 1998

morphological characteristics of the vastus lateralis muscle in COPD patients

  • C Simard, F Maltais, P Leblanc
  • Med Sci Sports Exerc
  • 1998

Gas exchange and cardiovascular kinetics upon different exercise protocols in heart transplant recipients

  • B Grassi, C Marconi, M Meyer
  • J Appl Physiol
  • 1997

Similar Papers

Loading similar papers…