Effect of hyperbaric oxygenation on intervertebral disc degeneration: an in vivo study with sprague-dawley rats.

@article{Wang2013EffectOH,
  title={Effect of hyperbaric oxygenation on intervertebral disc degeneration: an in vivo study with sprague-dawley rats.},
  author={I C Wang and H S Liu and Chung-Ming Yu and Shu-Wen Whu and S L Lin and Chun-I Su and Chih-Hwa Chen and Wen-Jer Chen},
  journal={Spine},
  year={2013},
  volume={38 3},
  pages={E137-42}
}
STUDY DESIGN An in vivo study was conducted to test the effect of hyperbaric oxygenation (HBO) on intervertebral disc degeneration in Sprague-Dawley rats. OBJECTIVE To observe the changes in intervertebral disc height and levels of glycosaminoglycan, collagen, interleukin-1β (IL-1β), prostaglandin E2 (PGE2), and inducible nitric oxide synthase (iNOS) in degenerated intervertebral discs after HBO therapy. SUMMARY OF BACKGROUND DATA Although the involvement of IL-1β, PGE-2, NO, and low O2… CONTINUE READING
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