Effect of hydroxyethyl starch 130/0.4 on blood loss and coagulation in patients with recent exposure to dual antiplatelet therapy undergoing off-pump coronary artery bypass graft surgery.

@article{Lee2011EffectOH,
  title={Effect of hydroxyethyl starch 130/0.4 on blood loss and coagulation in patients with recent exposure to dual antiplatelet therapy undergoing off-pump coronary artery bypass graft surgery.},
  author={Jeong Soo Lee and So Woon Ahn and Jong Wook Song and Jae Kwang Shim and Kyung-jong Yoo and Young Lan Kwak},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2011},
  volume={75 10},
  pages={2397-402}
}
BACKGROUND Hydroxyethyl starch (HES) solutions are often used for maintaining intravascular volume and improving microperfusion, while a large amount of HES can cause adverse effects on coagulation. As the indications for clopidogrel expand, an increasing number of patients undergoing off-pump coronary artery bypass surgery (OPCAB) are also undergoing dual antiplatelet therapy (DAPT), with its higher risk of bleeding complications. The aim of the present study was to determine whether a… CONTINUE READING