Effect of hydrogen peroxide on intracellular pH in the human atrial myocardium.

@article{Chao2002EffectOH,
  title={Effect of hydrogen peroxide on intracellular pH in the human atrial myocardium.},
  author={C Y Chao and Jong-Shiaw Jin and Chien-Sung Tsai and Yin Lan Tsai and Wei-Hwa Chen and Chao-Chin Chung and Shih-Hurng Loh},
  journal={The Chinese journal of physiology},
  year={2002},
  volume={45 3},
  pages={
          123-9
        }
}
The cardiac injury observed during myocardial ischemia and reperfusion has been shown to be a consequence of a complex mechanism in which the accumulation of hydrogen peroxide (H2O2) and other oxygen free radicals (OFRs), and intracellular pH (pHi) are believed to play a major role. However, the effect of H2O2 on pHi has not been well characterized in the human atrial myocardium. In the present study, we superfused hydrogen peroxide into the human atrial tissue in order to assess the effects of… CONTINUE READING

Similar Papers