Effect of human recombinant interleukin-2 on isolated rabbit femoral artery and porcine coronary artery and vein.

@article{Vedernikov1990EffectOH,
  title={Effect of human recombinant interleukin-2 on isolated rabbit femoral artery and porcine coronary artery and vein.},
  author={Yu. P. Vedernikov and T. Gr{\"a}ser and A Y Vedernikov and Alexander G. Tonevitsky},
  journal={Biomedica biochimica acta},
  year={1990},
  volume={49 7},
  pages={573-8}
}
Treatment of cancer patients with disseminating malignancy using human recombinant interleukin-2 (rIL-2) is usually complicated by some adverse effects such as hypotension, an increase in vascular permeability and water retention due to the so-called "capillary leak syndrome". Experiments on isolated vessels were carried out to study whether rIL-2 has some… CONTINUE READING