Effect of human papillomavirus type 16 oncogenes on MAP kinase activity.

  title={Effect of human papillomavirus type 16 oncogenes on MAP kinase activity.},
  author={Zheng Ming Gu and Greg Matlashewski},
  journal={Journal of virology},
  volume={69 12},
The mitogen-activated protein (MAP) kinase signal transduction pathway is an intracellular signaling cascade which mediates cellular responses to growth and differentiation factors. The MAP kinase pathway can be activated by a wide range of stimuli dependent on the cell types, and this is normally a transient response. Oncogenes such as ras, src, raf, and mos have been proposed to transform cells in part by prolonging the activated stage of components within this signaling pathway. The human… CONTINUE READING


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