Effect of human papillomavirus on cell cycle-related proteins p16, Ki-67, Cyclin D1, p53, and ProEx C in precursor lesions of cervical carcinoma: a tissue microarray study.

@article{ConesaZamora2009EffectOH,
  title={Effect of human papillomavirus on cell cycle-related proteins p16, Ki-67, Cyclin D1, p53, and ProEx C in precursor lesions of cervical carcinoma: a tissue microarray study.},
  author={Pablo Conesa-Zamora and Asunci{\'o}n Dom{\'e}nech-Peris and Francisco Javier Orantes-Casado and Sebasti{\'a}n Ortiz-Reina and Laura Sahuquillo-Fr{\'i}as and Jes{\'u}s Acosta-Ortega and Jos{\'e} Garc{\'i}a-Solano and Miguel P{\'e}rez-Guillermo},
  journal={American journal of clinical pathology},
  year={2009},
  volume={132 3},
  pages={378-90}
}
In-depth study of cell cycle proteins and human papillomavirus (HPV) genotyping can provide useful information about the malignant potential of precursor lesions of cervical carcinoma (CC). Immunostaining of cell cycle-related proteins (p16, cyclin D1, Ki-67, p53, and ProEx C) was evaluated using tissue microarrays, and HPV genotypes were identified in 144 cervical tissue specimens encompassing normal or benign epithelial lesions, low- and high-grade squamous intraepithelial lesions (LSIL and… CONTINUE READING