Effect of hindlimb unweighting on single soleus fiber maximal shortening velocity and ATPase activity.

@article{McDonald1993EffectOH,
  title={Effect of hindlimb unweighting on single soleus fiber maximal shortening velocity and ATPase activity.},
  author={Kerry S McDonald and Robert H Fitts},
  journal={Journal of applied physiology},
  year={1993},
  volume={74 6},
  pages={2949-57}
}
This study characterizes the time course of change in single soleus muscle fiber size and function elicited by hindlimb unweighting (HU) and analyzes the extent to which varying durations of HU altered maximal velocity of shortening (Vo), myofibrillar adenosinetriphosphatase (ATPase), and relative content of slow and fast myosin in individual soleus fibers. After 1, 2, or 3 wk of HU, soleus muscle bundles were prepared and stored in skinning solution at -20 degrees C. Single fibers were… CONTINUE READING
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