Effect of high glucose on peritoneal mesothelial cell biology.

@article{Ha2000EffectOH,
  title={Effect of high glucose on peritoneal mesothelial cell biology.},
  author={Hyo Shin Ha and Hi Bahl Lee},
  journal={Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis},
  year={2000},
  volume={20 Suppl 2},
  pages={S15-8}
}
OBJECTIVE This study reviews evidence that implicates high glucose (HG) in the pathogenesis of peritoneal fibrosis and proposes mechanisms potentially involved in the HG-induced peritoneal fibrosis that is observed in long-term peritoneal dialysis (PD) patients. DESIGN Selected Western literature is reviewed, examining the effect of HG on rat or human peritoneal mesothelial cell (HPMC) biology with particular reference to extracellular matrix (ECM) gene expression and protein synthesis… CONTINUE READING

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Activation of nuclear factor-κB in mesangial cells cultured under high glucose [Abstract

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1 Excerpt

High glucose-induced TGFβ1 and fibronectin synthesis by human peritoneal mesothelial cells: Involvement of PKC [Abstract

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High glucose-induced human peritoneal mesothelial cell synthesis of monocyte chemotactic protein-1 is mediated by protein kinase C [Abstract

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