Effect of high-dose vs standard-dose multivitamin supplementation at the initiation of HAART on HIV disease progression and mortality in Tanzania: a randomized controlled trial.

@article{Isanaka2012EffectOH,
  title={Effect of high-dose vs standard-dose multivitamin supplementation at the initiation of HAART on HIV disease progression and mortality in Tanzania: a randomized controlled trial.},
  author={Sheila Isanaka and Ferdinand M. Mugusi and Claudia A Hawkins and Donna Spiegelman and James Okuma and Said Aboud and Chalamilla Guerino and Wafaie Wahib Fawzi},
  journal={JAMA},
  year={2012},
  volume={308 15},
  pages={1535-44}
}
CONTEXT Large randomized trials have previously shown that high-dose micronutrient supplementation can increase CD4 counts and reduce human immunodeficiency virus (HIV) disease progression and mortality among individuals not receiving highly active antiretroviral therapy (HAART); however, the safety and efficacy of such supplementation has not been established in the context of HAART. OBJECTIVE To test the hypothesis that high-dose multivitamin supplementation vs standard-dose multivitamin… CONTINUE READING
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