Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects.

@article{Manning2004EffectOH,
  title={Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects.},
  author={Patrick J. Manning and Wayne H. F. Sutherland and Robert J Walker and Sheila M. Williams and Sylvia A. de Jong and Anne R. Ryalls and Elizabeth Anne Berry},
  journal={Diabetes care},
  year={2004},
  volume={27 9},
  pages={2166-71}
}
OBJECTIVE Markers of oxidative stress and plasma alanine transferase (ALT) levels are increased and circulating antioxidant concentrations are reduced in individuals with insulin resistance. Vitamin E improves glycemic control in people with diabetes. We tested the hypothesis that vitamin E would decrease markers of oxidative stress and plasma ALT levels and improve insulin sensitivity in overweight individuals. RESEARCH DESIGN AND METHODS Eighty overweight individuals (BMI >27 kg/m(2)) were… CONTINUE READING
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