Effect of high dietary manganese intake of neonatal rats on tissue mineral accumulation, striatal dopamine levels, and neurodevelopmental status.

Abstract

Mn is an essential element, but may become neurotoxic at high levels. Recent reports of high Mn levels in hair of children with neurodevelopmental deficits suggest that these deficits could be due to Mn-induced neurotoxic effects on brain dopamine (DA) systems, although the mechanism is not well understood. Infant formulas contain considerably higher… (More)

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@article{Tran2002EffectOH, title={Effect of high dietary manganese intake of neonatal rats on tissue mineral accumulation, striatal dopamine levels, and neurodevelopmental status.}, author={Trinh T. Tran and Winyoo Chowanadisai and Francis M. Crinella and Aleksandra Chicz-Demet and Bo L{\"{o}nnerdal}, journal={Neurotoxicology}, year={2002}, volume={23 4-5}, pages={635-43} }