Effect of hesperidin on mice bearing Ehrlich solid carcinoma maintained on doxorubicin

@article{Khedr2015EffectOH,
  title={Effect of hesperidin on mice bearing Ehrlich solid carcinoma maintained on doxorubicin},
  author={Naglaa F Khedr and Rania Khalil},
  journal={Tumor Biology},
  year={2015},
  volume={36},
  pages={9267-9275}
}
Doxorubicin (DOX) is widely used in cancer therapy of many carcinomas types. Unfortunately, DOX is not sufficiently effective in many cases, and increasing the dosage of it is limited due to its systemic toxicity. A citrus flavonoid hesperidin (HES) is proved to be potent antioxidant and protective agent against many diseases including cancer. In this context, the objective of this study was to examine effect of HES along with DOX on solid Ehrlich carcinoma (SEC) in mice. Forty male mice were… Expand
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