Effect of hemorrhagic shock duration on the activity of nuclear Ca2+/Mg(2+)-dependent DNA-endonucleases in canine cerebral cortex.

@article{Kozhura1994EffectOH,
  title={Effect of hemorrhagic shock duration on the activity of nuclear Ca2+/Mg(2+)-dependent DNA-endonucleases in canine cerebral cortex.},
  author={Vyacheslav Leontjevich Kozhura and Natalya Nosova and I. S. Novoderzhkina and J V Solovyeva},
  journal={Resuscitation},
  year={1994},
  volume={27 1},
  pages={67-71}
}
A direct correlation between the duration of arterial hypotension (40 mmHg) and the activity value of nuclear Ca2+/Mg(2+)-dependent DNA-endonucleases was revealed in dogs exposed to hemorrhagic shock. Thus, an increase in the activity of endonucleases was significant after 2 h of arterial hypotension. During that period there activity amounted to 4149… CONTINUE READING