Effect of heart failure on the mechanism of exercise-induced augmentation of mitral valve flow.

@article{Cheng1993EffectOH,
  title={Effect of heart failure on the mechanism of exercise-induced augmentation of mitral valve flow.},
  author={C P Cheng and Toshiyuki Noda and Takashi Nozawa and William James Little},
  journal={Circulation research},
  year={1993},
  volume={72 4},
  pages={795-806}
}
The exercise response of left ventricular (LV) filling dynamics may be altered by congestive heart failure (CHF). Accordingly, we studied 18 conscious dogs, instrumented to measure micromanometer LV and left atrial (LA) pressures and determine LV volume from three dimensions. CHF was produced by 4-5 weeks of right ventricular rapid pacing. Before CHF, exercise (5.5-8.5 mph for 8-15 minutes) increased the maximum rate of LV filling (dV/dtmax) (197 +/- 37 versus 297 +/- 56 ml/sec [mean +/- SD], p… CONTINUE READING

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Mechanism of augmented rate of left ventricle filling during exercise

  • Cheng C-P, Y Igarashi, WC Little
  • Circ Res
  • 1992

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