Effect of granulocyte-macrophage colony-stimulating factor on the generation of epidermal Langerhans cells.

@article{Burnham2000EffectOG,
  title={Effect of granulocyte-macrophage colony-stimulating factor on the generation of epidermal Langerhans cells.},
  author={Kim Burnham and Lorraine Robb and Clare L Scott and Meredith O'Keeffe and Ken D Shortman},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  year={2000},
  volume={20 12},
  pages={1071-6}
}
The role of granulocyte-macrophage colony-stimulating factor (GM-CSF) and Flt3 ligand in the in vivo development of Langerhans cells (LC) was assessed, considering both the steady-state levels of LC in the epidermis and the rate of LC recovery after depletion following lipopolysaccharide (LPS) treatment. The density of LC was determined by counting following IA-specific immunofluorescent staining of epidermal sections from mouse ears. LC levels were compared in beta common chain receptor null… CONTINUE READING

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