Effect of graded reductions in regional coronary perfusion on regional and total cardiac function.

@article{Wyatt1975EffectOG,
  title={Effect of graded reductions in regional coronary perfusion on regional and total cardiac function.},
  author={H L Wyatt and James S. Forrester and John V. Tyberg and S J Goldner and Samuel E. Logan and William W. Parmley and Harold James Swan},
  journal={The American journal of cardiology},
  year={1975},
  volume={36 2},
  pages={185-92}
}
This study examines the effects of graded reduction in regional coronary perfusion and changes in arterial oxygen concentration upon regional myocardial function and left ventricular function. In 14 open chest dogs, the distal left anterior descending coronary artery was cannulated and perfused at different pressures with blood equilibrated with either 21 or 95 percent oxygen, and regional function in the perfused myocardial segment was determined by use of the pressure-length loop. The mass of… CONTINUE READING
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