Effect of graded increases in smoke inhalation injury on the early systemic response to a body burn.

@article{Demling1995EffectOG,
  title={Effect of graded increases in smoke inhalation injury on the early systemic response to a body burn.},
  author={Robert H. Demling and Cheryl Lalonde and Yeo Kyu Youn and Lisa Picard},
  journal={Critical care medicine},
  year={1995},
  volume={23 1},
  pages={171-8}
}
OBJECTIVE To study the early (first 24 hrs) effect of increasing lung exposure to smoke on the hemodynamic response to a modest body burn. DESIGN A prospective randomized study. SETTING Laboratory at a university medical center. SUBJECTS Thirty-two adult yearling female sheep. INTERVENTIONS Adult sheep (n = 32) were given an 18% of body surface burn; 24 sheep were then exposed to cotton toweling smoke using 12 breaths of a tidal volume of 5, 10, or 20 mL/kg. Animals were awakened… CONTINUE READING

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