Effect of gonadal steroid receptors alterations on the pathophysiology of pelvic organ prolapse and urinary incontinence.

@article{Grigoriadis2016EffectOG,
  title={Effect of gonadal steroid receptors alterations on the pathophysiology of pelvic organ prolapse and urinary incontinence.},
  author={Chralampos Grigoriadis and Dimitrios K. Hassiakos and Panagiotis Bakas and Aliki Tympa and Constantinos P C Panoulis and Georgios Creatsas and Agathi I Kondi-Pafiti and Angelos E. Liapis},
  journal={Minerva ginecologica},
  year={2016},
  volume={68 1},
  pages={
          37-42
        }
}
BACKGROUND The aim of this study was to investigate the contribution of the gonadal steroid receptors expression to the pathophysiological pathways of pelvic organ prolapse (POP) and urodynamic stress urinary incontinence (USUI) after menopause. METHODS This was a prospective closely-matched controlled clinicopathological study. Immunohistochemistry for estrogen receptor isoform α (ER-α) and β (ER-β), as well as for progesterone receptor (PR), was performed on formaline-fixed and paraffin… CONTINUE READING

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Estrogen and Pelvic Organ Prolapse

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