Effect of gold nanoparticles on glutathione depletion-induced hydrogen peroxide generation and apoptosis in HL7702 cells.

@article{Gao2011EffectOG,
  title={Effect of gold nanoparticles on glutathione depletion-induced hydrogen peroxide generation and apoptosis in HL7702 cells.},
  author={Wen Gao and Kehua Xu and Lifei Ji and Bo Tang},
  journal={Toxicology letters},
  year={2011},
  volume={205 1},
  pages={86-95}
}
Gold nanoparticles (AuNPs) have shown promising biological and military applications due to their unique electronic and optical properties. However, little is known about their cytotoxicity when they come into contact with a biological system. The primary objective of this study is to determine the sequence of apoptotic signaling events that occur after modulation of the cellular redox state in HL7702 cells (human liver cell line), with emphasis on the role of the interaction of AuNPs with… CONTINUE READING