Effect of glycerol on intracellular virus survival: implications for the clinical use of glycerol-preserved cadaver skin.

@article{Marshall1995EffectOG,
  title={Effect of glycerol on intracellular virus survival: implications for the clinical use of glycerol-preserved cadaver skin.},
  author={L E Marshall and Manish M Ghosh and Stephen G. Boyce and Sheila MacNeil and Eric Freedlander and Goura Kudesia},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={1995},
  volume={21 5},
  pages={356-61}
}
Glycerol has long been used for the preservation of skin allografts. The antimicrobial activity of glycerol has not been fully documented. This paper reports the results of an investigation of a model studying the effect of glycerol on the inactivation of intracellular viruses. Two viruses--herpes simplex type I (HSV-1) and poliovirus--were cultured within human dermal fibroblasts. These intracellular viruses were incubated with 50 per cent, 85 per cent and 98 per cent glycerol at 4 degrees C… CONTINUE READING

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