Effect of glycaemic control on myocardial sympathetic innervation assessed by [123I]metaiodobenzylguanidine scintigraphy: a 4-year prospective study in IDDM patients

@article{Ziegler1998EffectOG,
  title={Effect of glycaemic control on myocardial sympathetic innervation assessed by [123I]metaiodobenzylguanidine scintigraphy: a 4-year prospective study in IDDM patients},
  author={Dan Ziegler and Frank Weise and K.-J. Langen and R. Piolot and Christian Boy and Achim Huebinger and H.-W. Mueller-Gaertner and Friedrich Arnold Gries},
  journal={Diabetologia},
  year={1998},
  volume={41},
  pages={443-451}
}
Diabetic cardiovascular autonomic neuropathy (CAN) has been directly characterized by reduced or absent myocardial [123I]metaiodobenzylguanidine (MIBG) uptake, but there is no information available on the relationship between the myocardial adrenergic innervation defects and long-term glycaemic control. In a prospective study over a mean of 4 years we examined myocardial sympathetic innervation in 12 Type 1 (insulin-dependent) diabetic patients using MIBG scintigraphy (absolute and relative… CONTINUE READING
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The effect of 8 years of strict glycaemic control on peripheral nerve function in IDDM patients: the Oslo Study

  • K-F Amthor, K Dahl-Jorgensen, TJ Berg
  • Diabetologia
  • 1994
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