Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.

@article{Gonzlez1998EffectOG,
  title={Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.},
  author={Mar{\'i}a Pilar Gonz{\'a}lez and Mar{\'i}a Trinidad Herrero and Susana Vicente and Mar{\'i}a Jes{\'u}s Oset-Gasque},
  journal={Neuroendocrinology},
  year={1998},
  volume={67 3},
  pages={181-9}
}
In this study, the effects of glutamate and glutamate receptor agonists in cultured chromaffin cells from bovine adrenal medulla were investigated. It was found that glutamate increases basal catecholamine (CA) secretion in a dose-dependent manner. This effect is mimicked by specific agonists of the four known glutamate receptors N-methyl-D-aspartate (NMDA), quisqualate/(RS)-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate (KA), and trans-(+)-1-amino-1,3-cyclopentane… CONTINUE READING

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