Effect of glucose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats.

@article{Dipette1986EffectOG,
  title={Effect of glucose on systemic hemodynamics and blood flow rate in normal and tumor tissues in rats.},
  author={Donald J Dipette and K A Ward-Hartley and Rakesh K. Jain},
  journal={Cancer research},
  year={1986},
  volume={46 12 Pt 1},
  pages={6299-304}
}
The effect of hyperglycemia on systemic hemodynamics and blood flow rate of Walker 256 carcinoma and several normal tissues of unanesthetized, unrestrained female Sprague-Dawley rats was measured, using the radioactive microsphere technique prior to and at 30 and 60 min after glucose administration (6 g/kg body weight i.v.). Whereas the mean arterial pressure and heart rate remained unchanged following glucose injection, cardiac output (CO), cardiac index, and stroke volume decreased by… CONTINUE READING