Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells.

@article{Lam1993EffectOG,
  title={Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells.},
  author={Man-yee Lam and George R Dubyak and Clark W. Distelhorst},
  journal={Molecular endocrinology},
  year={1993},
  volume={7 5},
  pages={686-93}
}
There is growing evidence for the involvement of Ca2+ in the programmed cell death (apoptosis) of lymphocytes, but the nature of glucocorticoid-induced Ca2+ fluxes and their role in the cell death pathway are poorly understood. In the study reported here, we assessed the effect of glucocorticoid treatment on intracellular Ca2+ homeostasis in W7MG1 mouse lymphoma cells. Levels of cytosolic Ca2+ were measured using the intracellular Ca2+ indicator fura2 AM, and total cellular Ca2+ was measured by… CONTINUE READING

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