Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.

@article{Jiang2005EffectOG,
  title={Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.},
  author={Xuemin Jiang and Kenneth Mapson Williams and Winston Spencer Liauw and Alaina J Ammit and Basil D. Roufogalis and Colin C. Duke and Richard O. Day and Andrew J. McLachlan},
  journal={British journal of clinical pharmacology},
  year={2005},
  volume={59 4},
  pages={425-32}
}
AIM The aim of this study was to investigate the effect of two common herbal medicines, ginkgo and ginger, on the pharmacokinetics and pharmacodynamics of warfarin and the independent effect of these herbs on clotting status. METHODS This was an open label, three-way crossover randomized study in 12 healthy male subjects, who received a single 25 mg dose of warfarin alone or after 7 days pretreatment with recommended doses of ginkgo or ginger from herbal medicine products of known quality… CONTINUE READING
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