Effect of gingerol on substance P and NK1 receptor expression in a vomiting model of mink.

@article{Qian2010EffectOG,
  title={Effect of gingerol on substance P and NK1 receptor expression in a vomiting model of mink.},
  author={Qiu-hai Qian and Wang Jin Yue and Wen-hui Chen and Zhi-Hong Yang and Zhan-tao Liu and Yao-xia Wang},
  journal={Chinese medical journal},
  year={2010},
  volume={123 4},
  pages={478-84}
}
BACKGROUND Gingerol is the generic term for pungent constituents in ginger, which has been reported to be effective for inhibiting vomiting. We attempted to investigate the antiemetic effect of gingerol and its effective mechanism on substance P and NK(1) receptors in minks. METHODS The antiemetic effect of gingerol was investigated during a 6-hour observation on a vomiting model in minks induced by cisplatin, (7.5 mg/kg, intraperitoneal). The distribution of substance P and NK(1) receptors… CONTINUE READING
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