Effect of ghrelin on gonadotrophin secretion in women during the menstrual cycle.

  title={Effect of ghrelin on gonadotrophin secretion in women during the menstrual cycle.},
  author={Christina I. Messini and Konstantinos C Dafopoulos and Nektarios Chalvatzas and Panagiotis Georgoulias and Ioannis E Messinis},
  journal={Human reproduction},
  volume={24 4},
BACKGROUND It has been suggested that ghrelin may affect reproduction in animals by decreasing pituitary LH secretion. The role of ghrelin on LH secretion in women has not been investigated. Our aim was to assess the effect of ghrelin administration on basal and GnRH-induced LH secretion during the menstrual cycle. METHODS Normally cycling women (n = 10) received on Day 3 of three consecutive cycles a single bolus i.v. of either ghrelin (1 microg/kg, cycle 1) or GnRH (100 microg, cycle 2) or… CONTINUE READING

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