Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer.

@article{Furuta1998EffectOG,
  title={Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer.},
  author={T Furuta and K Ohashi and Takahiro Kamata and Misako Takashima and Kazuhiro Kosuge and Takatoshi Kawasaki and Hiroyuki Hanai and Tsuyoshi Kubota and Tetsuo Ishizaki and Eri Kaneko},
  journal={Annals of internal medicine},
  year={1998},
  volume={129 12},
  pages={1027-30}
}
Eradication of Helicobacter pylori is very efficacious in the treatment of upper gastrointestinal disease [1-3]. Current strategies for the cure of H. pylori infection include triple therapy with a proton-pump inhibitor, amoxicillin, and clarithromycin or metronidazole [1-6], but the development of resistance of H. pylori to the latter two drugs has been reported [7-9]. Although dual therapy with omeprazole and amoxicillin achieves somewhat lower cure rates for H. pylori infection [4, 6], it… CONTINUE READING

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Helicobacter pylori infection

  • CS Goodwin, M MMendall, TC. Northfield
  • 1997
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