Effect of gellan gum on the thermogelation property and drug release profile of Poloxamer 407 based ophthalmic formulation.

Abstract

The effect of gellan gum on the gelation behavior and in-vitro release of a specific drug named pilocarpine hydrochloride from different ophthalmic formulations based on poloxamer 407 is examined. The mixture of 0.3wt% gellan gum and 18wt% poloxamer (PM) solutions show a considerable increase in gel strength in physiological condition. Gel dissolution rate… (More)
DOI: 10.1016/j.ijbiomac.2017.03.194

Cite this paper

@article{Dewan2017EffectOG, title={Effect of gellan gum on the thermogelation property and drug release profile of Poloxamer 407 based ophthalmic formulation.}, author={Mitali Dewan and Gunjan Sarkar and Manas Bhowmik and Beauty Das and Atis Kumar Chattoapadhyay and Dipak Rana and Dipankar Chattopadhyay}, journal={International journal of biological macromolecules}, year={2017}, volume={102}, pages={258-265} }