Effect of gelatinase inhibition on adipogenesis and adipose tissue development.

Abstract

1. The potential of the matrix metalloproteinase (MMP) inhibitor ABT-518 to affect pre-adipocyte differentiation in vitro and adipose tissue development in vivo was investigated using mouse models of adipogenesis and obesity. 2. Differentiation of 3T3-F442A pre-adipocytes into mature adipocytes was enhanced in a dose-dependent manner by the addition of ABT… (More)
DOI: 10.1111/j.1440-1681.2011.05635.x

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Cite this paper

@article{Hul2012EffectOG, title={Effect of gelatinase inhibition on adipogenesis and adipose tissue development.}, author={Matthias Van Hul and Dries Bauters and Uwe Himmelreich and Nele Kindt and Bernard Noppen and Marc Vanhove and Henri Roger Lijnen}, journal={Clinical and experimental pharmacology & physiology}, year={2012}, volume={39 1}, pages={49-56} }