Effect of gamma irradiation on toxicity and immunogenicity of Androctonus australis hector venom.

@article{Abib2003EffectOG,
  title={Effect of gamma irradiation on toxicity and immunogenicity of Androctonus australis hector venom.},
  author={Lila Boussag Abib and Fatima Laraba-Djebari},
  journal={Canadian journal of physiology and pharmacology},
  year={2003},
  volume={81 12},
  pages={
          1118-24
        }
}
An investigation was made of the radiosensitivity of the toxic and immunological properties of Androctonus australis hector venom. This venom was irradiated with two doses of gamma rays (1 and 2 kGy) from a 60Co source. The results showed that venom toxicity was abolished for the two radiation doses (1 and 2 kGy) with, respectively, 10 and 25 times its initial LD50 value. However, irradiated venoms were immunogenic, and the antibodies elicited by them were able to recognize the native venom by… CONTINUE READING
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