Effect of furazolidone on sister-chromatid exchanges, cell proliferation kinetics, and mitotic index in vivo and in vitro.

Abstract

Furazolidone is an antimicrobial compound used in human and veterinary medicine. The aim of this investigation was to determine its genotoxic capacity in vitro and in vivo. We used the human lymphocyte culture system to detect the effect of 2.0, 4.0, 6.0, 8.0, or 10.0 micrograms/ml, and the mouse bone marrow assay to determine the effect of 8.6, 30.0, or 75… (More)

Topics

Cite this paper

@article{MadrigalBujaidar1997EffectOF, title={Effect of furazolidone on sister-chromatid exchanges, cell proliferation kinetics, and mitotic index in vivo and in vitro.}, author={Eduardo Madrigal-Bujaidar and Juan Carlos Cambera Iba{\~n}ez and Morena Cassani and Germ{\'a}n A Chamorro}, journal={Journal of toxicology and environmental health}, year={1997}, volume={51 1}, pages={89-96} }