Effect of freeze-thawing and polyethylene glycol (PEG) lipid on fusion and fission of phospholipid vesicles.

@article{Sriwongsitanont2004EffectOF,
  title={Effect of freeze-thawing and polyethylene glycol (PEG) lipid on fusion and fission of phospholipid vesicles.},
  author={S. Sriwongsitanont and Masaharu Ueno},
  journal={Chemical & pharmaceutical bulletin},
  year={2004},
  volume={52 5},
  pages={
          641-2
        }
}
  • S. Sriwongsitanont, Masaharu Ueno
  • Published 2004
  • Chemistry, Medicine
  • Chemical & pharmaceutical bulletin
  • The effect of freeze-thawing on the size of egg yolk phosphatidylcholine (EggPC) vesicles in the presence of 0-40 mol% distearoylphosphatidylethanolamine-polyethylene glycol 2000 (DSPE-PEG) was studied. Mean diameters of the vesicles fell into a range of 80-150 nm after 10 times freeze-thawing in spite of their original size. In the process of freeze-thawing, two opponent events, one is fission and the other is fusion, occurred at the same time. DSPE-PEG accelerated the fusion event. 
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