Effect of four medicinal plants on amyloid-β induced neurotoxicity in SH-SY5Y cells.

  title={Effect of four medicinal plants on amyloid-β induced neurotoxicity in SH-SY5Y cells.},
  author={Emanuel A Adewusi and Gerda Fouche and Vanessa Steenkamp},
  journal={African journal of traditional, complementary, and alternative medicines : AJTCAM},
  volume={10 4},
Amyloid-beta peptide (Aβ) is implicated in the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disorder. This study was designed to determine the effect of four medicinal plants used to treat neurodegenerative diseases on Aβ-induced cell death. Cytotoxicity of the ethanol extracts of the plants was determined against SH-SY5Y (human neuroblastoma) cells which were untreated, as well as toxically induced with Aβ, using the MTT and neutral red uptake assays. Cell viability was… CONTINUE READING
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