Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults.

@article{Courtney2004EffectOF,
  title={Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults.},
  author={Rachel Courtney and David Wexler and Elaine Radwanski and Josephine Lim and Mark M Laughlin},
  journal={British journal of clinical pharmacology},
  year={2004},
  volume={57 2},
  pages={218-22}
}
AIMS This randomized, crossover, single-dose study evaluated the relative oral bioavailability of posaconazole suspension and coprecipitate tablet formulations. Additionally, the study determined whether systemic exposure to posaconazole was affected by prandial status or by the fat content of a meal. METHODS This was a randomized, open-label, four-way crossover, single-dose study in 20 healthy men. Posaconazole pharmacokinetics were evaluated over 72 h following a single oral dose of… CONTINUE READING
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Effects of food on clinical pharmacokinetics

  • BN Singh
  • Clin Pharmacokinet
  • 1999

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