Effect of food and antacid on absorption of orally administered ticlopidine hydrochloride.

Abstract

Ticlopidine is a potent inhibitor of platelet aggregation. Absorption of ticlopidine after oral dosing is rapid and complete. Ticlopidine is extensively metabolized with a relative minor component of unchanged ticlopidine in plasma. The randomized crossover study described here was undertaken to examine the effect of food and antacid on the oral… (More)

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@article{Shah1990EffectOF, title={Effect of food and antacid on absorption of orally administered ticlopidine hydrochloride.}, author={Jigesh Shah and A Fratis and Demetrius E Ellis and Shigeto Murakami and Philip Teitelbaum}, journal={Journal of clinical pharmacology}, year={1990}, volume={30 8}, pages={733-6} }