Effect of follicular fluid oxidative stress on meiotic spindle formation in infertile women with polycystic ovarian syndrome.

@article{Chattopadhayay2010EffectOF,
  title={Effect of follicular fluid oxidative stress on meiotic spindle formation in infertile women with polycystic ovarian syndrome.},
  author={Ratna Chattopadhayay and Ashalatha Ganesh and Jayanta Samanta and Saikat Kumar Jana and Baldya Nath Chakravarty and Koel Chaudhury},
  journal={Gynecologic and obstetric investigation},
  year={2010},
  volume={69 3},
  pages={197-202}
}
BACKGROUND The effect of follicular fluid (FF) oxidative stress (OS) on meiotic spindle (MS) formation in oocytes and subsequent outcome in women with polycystic ovarian syndrome (PCOS) are evaluated in this study. METHODS 326 oocytes from 35 PCOS women (group A) and 208 oocytes from 32 women with tubal infertility (group B) were visualized for MS using PolScope. FF was analyzed for OS markers including reactive oxygen species (ROS), lipid peroxidation and total antioxidant capacity (TAC… CONTINUE READING
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