Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: A systematic review

  title={Effect of folate supplementation on folate status and health outcomes in infants, children and adolescents: A systematic review},
  author={Szimonetta Lohner and Katalin Fekete and Cristiana Berti and Mar{\'i}a Hermoso and Irene Cetin and Berthold V. Koletzko and Tamás Decsi},
  journal={International Journal of Food Sciences and Nutrition},
  pages={1014 - 1020}
The aim of this systematic review was to collect all available randomized controlled trials on the effect of folate supplementation on folate status and health outcomes within the paediatric age group. The method included a structured search strategy on MEDLINE, Embase and Cochrane databases, with formal inclusion/exclusion criteria and data extraction procedure. We included 26 studies. We conclude that both serum and erythrocyte folate values reflect folate intake; however, serum folate reacts… 

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