Effect of fluphenazine on the footshock-induced opioid analgesia and leu-enkephalin concentration in the rat brain.

Abstract

The effect of post-shock injection of 5 mg/kg fluphenazine on stress-induced analgesia (tail immersion test) and leu-enkephalin content in discrete brain areas (radioimmunoassay) was studied in male Wistar rats. The stress-induced analgesia, which was naloxone-reversible, was attenuated and shortened by fluphenazine, the drug also antagonized the stress… (More)

Topics

Cite this paper

@article{Kowalski1988EffectOF, title={Effect of fluphenazine on the footshock-induced opioid analgesia and leu-enkephalin concentration in the rat brain.}, author={Jens T. Kowalski and Malwina A. Huzarska and Rejeanna M Jasinski}, journal={Polish journal of pharmacology and pharmacy}, year={1988}, volume={40 6}, pages={621-5} }