Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot study.

  title={Effect of fluoxetine on regional cerebral metabolism in autistic spectrum disorders: a pilot study.},
  author={Monte S. Buchsbaum and Eric Hollander and M. Mehmet Haznedar and Cheuk Tang and Jacqueline L. Spiegel-Cohen and Tek C. Wei and Andrea Solimando and Bradley R. Buchsbaum and Diana Robins and Carol A. Bienstock and Charles Cartwright and Serge A Mosovich},
  journal={The international journal of neuropsychopharmacology},
  volume={4 2},
The regional metabolic effects of fluoxetine were examined in patients with autism spectrum disorders. Six adult patients with DSM-IV and Autism Diagnostic Interview (ADI) diagnoses of autism (n = 5) and Asperger's syndrome (n = 1), entered a 16-wk placebo-controlled cross-over trial of fluoxetine. The patients received (18)F-deoxyglucose positron emission tomography with co-registered magnetic resonance imaging at baseline and at the end of the period of fluoxetine administration. After… CONTINUE READING
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