Effect of fish oil on cognitive performance in older subjects

@article{Rest2008EffectOF,
  title={Effect of fish oil on cognitive performance in older subjects},
  author={O. van de Rest and J. Geleijnse and F. Kok and W. V. van Staveren and C. Dullemeijer and M. Olderikkert and A. Beekman and C. P. de Groot},
  journal={Neurology},
  year={2008},
  volume={71},
  pages={430 - 438}
}
Background: High intake of n-3 polyunsaturated fatty acids may protect against age-related cognitive decline. However, results from epidemiologic studies are inconclusive, and results from randomized trials in elderly subjects without dementia are lacking. Objective: To investigate the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation on cognitive performance. Methods: Double-blind, placebo-controlled trial involving 302 cognitively healthy (Mini-Mental State… Expand
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TLDR
Fish including oily fish could be advised as part of a balanced diet for public health purpose, although the evidence for better cognition is only fairly consistent and it is unlikely that n-3 FA will emerge as a treatment option in general for improving cognitive function in patients with Alzheimer's disease. Expand
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TLDR
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It is suggested that n‐3 fatty acids in the diet and adherence to the MedDiet are beneficial in slowing age‐related cognitive decline, however, more high‐quality RCTs would be useful to clarify the effect of n-3 fatty acid supplements on cognition. Expand
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TLDR
Elevating depleted levels of EPA and DHA through supplementation in individuals with CIND or AD was found to have negligible beneficial effect on their cognition or mood, confirming an overall negligible benefit of omega-3 PUFA supplementation for those with cognitive impairment and dementia. Expand
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As the process of Alzheimer's disease (AD) begins years before disease onset, searching for prevention strategies is of major medical and economic importance. Nutritional supplementation withExpand
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Few studies to support or refute the evidence that w3-PUFA supplementation in patients aged 65 or older improves cognitive performance or prevents dementia are found. Expand
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