Effect of finasteride on adrenal steroidogenesis in men.

  title={Effect of finasteride on adrenal steroidogenesis in men.},
  author={R. Rittmaster and L. Antonian and M. New and E. Stoner},
  journal={Journal of andrology},
  volume={15 4},
  • R. Rittmaster, L. Antonian, +1 author E. Stoner
  • Published 1994
  • Medicine
  • Journal of andrology
  • Finasteride, a 5 alpha-reductase inhibitor, does not bind to the androgen receptor and has no other known hormonal activity. To determine what effect, if any, it has on adrenal steroidogenesis, 10 healthy men received 5 mg finasteride daily for 28 days. Adrenocorticotropic hormone (ACTH) stimulation tests were performed before and after 4 weeks of finasteride administration (5 mg daily). Serum levels of 17-hydroxypregnenolone, 17-hydroxyprogesterone, deoxycorticosterone, corticosterone… CONTINUE READING
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