Effect of ferric sorbitol citrate (FSC) administration on NF-kappaB in macrophages and spleen cells of rats.

Abstract

Interaction of iron metabolism and the immune system is complex and pathological changes in one system affect the other. Ferric sorbitol citrate (FSC), non-toxic compound of ferric ions with sorbitol and citrate. has immunomodulatory effect in treated mice. We investigated an effect of FSC on NF-kappaB expression/activation in peritoneal macrophages and… (More)

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