Effect of fenofibrate on LDL-induced endothelial dysfunction in rats

@article{Yang2004EffectOF,
  title={Effect of fenofibrate on LDL-induced endothelial dysfunction in rats},
  author={Tian-lun Yang and Meifang Chen and Bai-Ling Luo and Jing Yu and Jun-Lin Jiang and Yuan‐jian Li},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2004},
  volume={370},
  pages={79-83}
}
Previous investigations have demonstrated that asymmetric dimethylarginine (ADMA) is an important factor contributing to endothelial dysfunction, and that fenofibrate has a protective effect on the endothelium in hyperlipidaemic patients. In the present study in rats treated with native low-density lipoprotein (nLDL), we addressed the question of whether the beneficial effect of fenofibrate on endothelial cells is related to reduction of the ADMA concentration. A single injection of nLDL (4 mg… 
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EFFECT OF FENOFIBRATE ON THE LEVEL OF ASYMMETRIC DIMETHYLARGININE IN TYPE 2 DIABETES MELLITUS
TLDR
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