Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae.

@article{Chatterjee2007EffectOF,
  title={Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae.},
  author={Arpita Chatterjee and Pradeep K Dutta and Rukhsana Chowdhury},
  journal={Infection and immunity},
  year={2007},
  volume={75 4},
  pages={1946-53}
}
Bile induces pleiotropic responses that affect production of virulence factors, motility, and other phenotypes in the enteric pathogen Vibrio cholerae. Since bile is a heterogeneous mixture, crude bile was fractionated, and the components that mediate virulence gene repression and enhancement of motility were identified by nuclear magnetic resonance, gas chromatography (GC), and GC-mass spectrometry analyses. The unsaturated fatty acids detected in bile, arachidonic, linoleic, and oleic acids… CONTINUE READING

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