Effect of fasudil on growth, adhesion, invasion, and migration of 95D lung carcinoma cells in vitro.

@article{Yang2010EffectOF,
  title={Effect of fasudil on growth, adhesion, invasion, and migration of 95D lung carcinoma cells in vitro.},
  author={Xueying Yang and Yang Zhang and Shumin Wang and Wenjun Shi},
  journal={Canadian journal of physiology and pharmacology},
  year={2010},
  volume={88 9},
  pages={874-9}
}
The objective of the study was to investigate the effects of a Rho-kinase inhibitor on 95D lung carcinoma cell growth, adhesion, invasion, and migration and to explore the underlying molecular mechanisms involved in this process. After treatment of 95D lung carcinoma cells with fasudil, an inhibitor of Rho-kinase, cell biological behaviors such as growth, adhesion, invasion, and migration were observed. Matrix metalloproteinase (MMP) activity and Western blot assay were used to evaluate… CONTINUE READING
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