Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans.

@article{Navarathna2007EffectOF,
  title={Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans.},
  author={Dhammika H Navarathna and Jacob Michael Hornby and Navasona Krishnan and Anne M. Parkhurst and Michelle R. Mathiesen and Kenneth W. Nickerson},
  journal={Infection and immunity},
  year={2007},
  volume={75 4},
  pages={
          1609-18
        }
}
This work extends our previous observation that the fungus Candida albicans secretes micromolar levels of farnesol and that accumulation of farnesol in vitro prevents the yeast-to-mycelium conversion in a quorum-sensing manner. What does farnesol do in vivo? The purpose of this study was to determine the role of farnesol during infection with a well-established mouse model of systemic candidiasis with C. albicans A72 administered by tail vein injection. This question was addressed by altering… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 61 REFERENCES

Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans

Oh, K.-B, H. Miyazawa, T. Naito, H. Matsuoka
  • Proc. Natl. Acad. Sci. USA
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol.

  • Applied and environmental microbiology
  • 2001
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Host recognition by Candida species, p. 67–86

R. Calderone, N.A.R. Gow
  • 2002
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Host recognition by Candida species, p. 67–86

R. Calderone, N.A.R. Gow
  • 2002
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans

Oh, K.-B, H. Miyazawa, T. Naito, H. Matsuoka
  • Proc. Natl. Acad. Sci. USA
  • 2001
VIEW 4 EXCERPTS
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