Effect of factor Xa inhibitors on the platelet-derived microparticles procoagulant activity in vitro and in vivo in rats.

@article{Hrault2000EffectOF,
  title={Effect of factor Xa inhibitors on the platelet-derived microparticles procoagulant activity in vitro and in vivo in rats.},
  author={J P H{\'e}rault and Bertrand Perrin and C Jongbloet and A M Pflieger and Andr{\'e} Bernat and J. J. Herbert},
  journal={Thrombosis and haemostasis},
  year={2000},
  volume={84 4},
  pages={668-74}
}
The aim of this study was to investigate the effect of factor Xa inhibitors on the prothrombinase activity of platelet-derived microparticles in vitro and in vivo. The factor Xa inhibitors studied were DX9065A (a direct factor Xa inhibitor) and Sanorg34006 (an antithrombin (AT)-mediated factor Xa inhibitor). Microparticles formed from the platelet surface… CONTINUE READING