Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study

@article{Gauderman2007EffectOE,
  title={Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study},
  author={W. Gauderman and H. Vora and R. McConnell and K. Berhane and F. Gilliland and Duncan C. Thomas and F. Lurmann and E. Avol and N. Kunzli and M. Jerrett and J. Peters},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={571-577}
}
BACKGROUND Whether local exposure to major roadways adversely affects lung-function growth during the period of rapid lung development that takes place between 10 and 18 years of age is unknown. This study investigated the association between residential exposure to traffic and 8-year lung-function growth. METHODS In this prospective study, 3677 children (mean age 10 years [SD 0.44]) participated from 12 southern California communities that represent a wide range in regional air quality… Expand
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Exposure to traffic-related air pollution during infancy affects lung function in children up to 8 years of age and particularly in those sensitized to common inhalant or food allergens. Expand
Early-Life Exposure to Traffic-related Air Pollution and Lung Function in Adolescence.
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Exposure to traffic-related air pollution in infancy is negatively associated with FEV1 at age 16 years, leading to increased risk of clinically important deficits. Expand
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The current epidemiological evidence on the effect of traffic-related air pollution on lung function in children and adolescents is summarized, focusing in particular on time windows of exposure, small airway involvement, and vulnerable sub-groups in the population. Expand
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Air pollution exposure may lead to increased airway obstruction, but not reduced lung volume in adolescence, and Associations with FEV1 were stronger in boys than girls and were not modified by asthma status. Expand
Traffic exposure and lung function in adults: the Atherosclerosis Risk in Communities study.
TLDR
Higher traffic density was significantly associated with lower forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) in women and this is the largest published study of traffic exposure and pulmonary function in adults to date. Expand
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Long-term improvements in air quality were associated with statistically and clinically significant positive effects on lung-function growth in children and these associations persisted after adjustment for several potential confounders. Expand
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Exposure to road-traffic PM10 during pregnancy may result in small but significant reductions in lung function at age 8 years, and at age 15 years, no adverse associations were seen with lung function. Expand
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